Here is some technical information from one
of our R&D partners:
NMR ANALYSIS OF WATER MOLECULE CLUSTERS
Nuclear magnetic resonance spectroscopy (NMR) was first developed in 1946 by
research groups at Stanford and M.I.T., in the USA. The radar technology
developed during World War II made many of the electronic aspects of the NMR
spectrometer possible.
With the newly developed hardware physicists and chemists began to apply the
technology to chemistry and physics problems.
Over the next 50 years NMR developed into the premier organic spectroscopy
available to chemists to determine the detailed chemical structure of the
chemicals they were synthesizing. Another well-known product of NMR technology
has been the Magnetic Resonance Imager (MRI), which is utilized extensively in
the medical radiology field to obtain image slices of soft tissues in the human
body.
In recent years, NMR has moved out of the research laboratory and into the
on-line process analyzer market. This has been made possible by the production
of stable permanent magnet technologies that allow high-resolution 1H NMR
spectra to be obtained in a process environment.
NMR analytical technique therefore provides useful data regarding the type,
quantity and arrangement of different atoms in chemical systems, liquids and
solids. NMR is a critical technique for structure determination, often required
on short notice, many times in medical emergencies and diagnostics.
An extensive range of NMR laboratory analytical measurements can be made in the
following general categories:
* Compound identity
* Structure shape and bonding(including water crystalline characteristics)
* Mixture component composition
* Atomic composition
* Molecular weight, Molecular formulae
* Polymer composition
* Polymer arrangement
* Molecular motion
* Inter-molecular exchange processes
* Intra-molecular exchange processes
* Low and high temperature effects
* Basic chemical functionality of a sample
* 2d NMR, Structural detail, connectivity, correlation spectroscopy
* Conformation of a molecule, Nuclear Overhauser Effect, (NOE)
NMR has been used by a wide range of laboratories and degreed scientists
involved in biochemistry, neurobiological studies and general water chemistry to
evaluate the various physical characteristics of water molecules and their
relationships to one another before and after “processing” or exposure to
various physical and electromagnetic stimuli.
NMR analysis of various organic compounds, water structures and other materials
involves a fairly detailed understanding of signal transmission and processing
theory, including the use of Fourier Transforms. In general terms, a signal of
known bandwidth is transmitted toward a “target” which has unknown chemical or
structural characteristics. Depending on how the “target” reacts to this
incoming signal, scientists can determine a considerable amount about the
composition of the unknown material, compound or molecular structure.
Since the target material is composed of molecules which have electromagnetic
characteristics of their own, significant information is obtained by determining
how long it takes to have the target material return to its “normal”
electromagnetic state after it has been stimulated by the incoming, transmitted
frequency or frequencies. This is called the “relaxation time” and in the case
of water has been directly correlated with the amount or number of water
molecules which are clustered to together and which(as a group) return to their
normal electromagnetic state after external stimulation by the incoming signal.
The larger the group of water molecules, the longer the “relaxation time”; the
smaller the group of molecules in the cluster, the shorter the relaxation time.
A similar but somewhat more complicated analytical representation is used in
non-invasive MRI analysis of various body tissues, tumor identification and
other physiological conditions at a cellular level. Similar in many respects to
the radar system example identified at the top of this page, the relaxation
times of the various reflected or “resonant” returned signals allow the medical
technician to identify the various body components being targeted by the
transmitted signal(s).
“Clustered” water is typically characterized by smaller groups of molecules,
lower surface tensions and thus can more easily penetrate the cellular membrane.
This clustering process is somewhat akin to the ease of carrying a bowling ball
through a normal doorway versus trying to carry an 8 foot diameter balloon
through the same doorway.
As a result, cellular absorption is limited to materials which have
exceptionally small metrics. Materials which cannot pass through the membrane
remain in the extracellular fluids as electrolytes or waste products.
Our body certainly needs electrolytes to conduct electrical signals between
individual body cells but unless water can pass through the membrane into the
cell, the cell dehydrates and dies; no oxygen or hydrogen is available inside
the cell to assist in metabolism of various proteins and carbohydrates and the
cell dies; and if water cannot pass into the cell, detoxification or cleansing
of the cell does not take place and the cell dies due to cumulative toxicity and
the body as a whole thus suffers due to the inability of cells to expel toxic
waste material.
It is quite similar to having an automobile without a carbureutor or exhaust
system: fuel (water) cannot enter the engine and toxic waste products (carbon
monoxide) cannot leave the engine. The result is quite predictable for the
automobile and of course similar in the case of animals and humans subjected the
same restrictions.
So, what type of water more easily penetrates cellular membranes and nourishes
the cells and what type(s) of water simply cannot get past the “gatekeeper” due
to their characteristics or materials which the water molecules are carrying as
they enter the bloodstream?
It has been determined by Lorenzen, Jhon and others that water molecules
clustered in groups of 5, 6 and 7 molecules tend to pass through the membrane
more easily then larger groups. It reminds me of the recent “le Tour de France”
when the bicyclists encountered a narrow road they organized into a single file
column. When the road widened, they returned to racing several abreast. The
narrow road in effect represents the small channels in the cellular membrane
through which nutrients and water can pass. The figure below illustrates the
idea.
So, NMR can help us identify materials and water characteristics which permit
efficient nutrient transfer as well as efficienty hydration. A typical NMR
electronic “radar return signal” is illustrated below.
This type of response or relaxation time indicates that the water clusters are
small compared to other types of water containing a variety of inorganic
minerals or other materials where the half width of the relaxation time response
is considerably larger, up to and including responses in excess of twice the
amount illustrated above.
Other portions of this website include information on how water can be
conditioned so that narrow NMR signals as illustrated above can be realized.
Such waters are thus more easily transferred into cells and widely accepted
measurement techniques for measuring cellular water content (RJM instrumentation,
for example) can easily demonstrate this hydration effect.
Be thankful that science is now capable of giving us some indications of not
only what types of foods are healthy for our body but also what types and
characteristics of our drinking water are best suited for effective hydration of
our body’s billions of cells.
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